triptolide相关论文
...
雷公藤内酯醇(triptolide),又称雷公藤内酯、雷公藤甲素,是从卫矛科雷公藤属雷公藤(tripterygium wilfordii Hook.F)、昆明山海棠[......
目的:以聚乙二醇单硬脂酸酯表面修饰材料结合到固体脂质纳米粒(solid lipid nanoparticles,SLN),以雷公藤内酯醇(triptolide,TPL)......
目的 探讨雷公藤内酯醇(TP)对人胰腺癌PANC1细胞株侵袭能力的影响及其与Toll样受体4/核因子-KB(TLR4/NF-KB)信号通路的关系.方法 ......
Effects of Triptolide on the Expression and Activity of NF-κB in Synovium of Collagen-induced Arthri
The expression and activity of NF-κB in the synovium of collagen-induced arthritis (CIA)rats was detected in order to i......
目的研究雷公藤内酯醇生物贴的体外经皮吸收特点。方法利用改良Franz扩散池研究雷公藤内酯醇生物贴的经皮吸收特点,以HPLC法测定雷......
Recent studies indicate that cell-cycle checkpoints are tightly correlated with the regulation of apoptosis, in which p5......
雷公藤内酯醇（triptolide）是从福建省泰宁县产的雷公藤根皮中分离提取的有效成分，我所经实验及临床Ⅰ、Ⅱ期研究发现其对多种髓系及淋......
目的研究雷公藤甲素自微乳对荷人前列腺癌PC-3细胞裸鼠移植瘤的抑制作用。方法构建荷人前列腺癌PC-3细胞裸鼠移植瘤,分为模型组、......
目的:建立高效液相色谱法测定复方雷公藤糖浆中雷公藤甲素的方法。方法:采用Diamonsil C18(150 mm×4.6 mm,5μm)色谱柱分离,甲醇-......
目的研究糖尿病大鼠肾皮质RANTES和desmin表达及雷公藤内酯醇对其干预作用。方法 SD大鼠随机分为正常组(NG)、模型组(DM)和小、大......
Effects of Triptolide on the Expression and Activity of NF-κB in Synovium of Collagen-induced Arthri
The expression and activity of NF-κB in the synovium of collagen-induced arthritis (CIA)rats was detected in order to i......
Relationship between Single Nucleotide Polymorphism in TNF-α Gene Promoter Region and Inhibitory Eff
The relationship between tumour necrosis factor-α (TNF-α) gene polymorphism and inhibitory effects of triptolide on TN......
Effect of Triptolide on Expression of Receptor Activator of Nuclear Factor-κB Ligand in Rat Adjuvant
The effect of triptolide (TP) on the expression of receptor activator of nuclear factor-κB ligand (RANKL) and osteoprot......
Objective Tripterygium wilfordii Hook. f. has been used for centuries in traditional Chinese medicine to treat autoimmun......
The Proteasomal Inhibitor MG132 Potentiates Apoptosis of Triptolide-Treated K562 Cells by Regulating
OBJECTIVE To explore the anticancer mechanism of triptolide in human leukemia K562 cells,and to further determine whethe......
目的研究雷公藤甲素(TP)对大鼠蛛网膜下腔出血(SAH)后的脑保护作用及其机制。方法48只雄性SD大鼠，在西安交通大学医学部动物实验中......
Astrocytes in an in vitro murine astrocyte model of oxygen and glucose deprivation/hypoxia and reoxygenation were treate......
目的 以抑癌基因即腺瘤性结肠息肉病相关基因(APE)存在异常甲基化的急性T淋巴细胞白血病Jurkat细胞为研究对象,探究雷公藤内酯醇(T......
目的 观察雷公藤甲素对2型糖尿病(T2DM)大鼠肾组织足细胞Nephrin、Podocin蛋白表达的影响及其机制探讨.方法 SPF级雄性8周龄Wistar......
Bootstrapping estimates of regression analysis for a non-random sample and its application in the re
Objective: To solve the problem of parameter estimate in the regression analysis of non-random sample. Methods: Calculat......
目的 研究雷公藤甲素洗脱支架抑制血管新生内膜增殖的有效性、对内皮功能的影响及支架安全性. 方法 将16只冠状动脉再狭窄模型小型......
This paper reviewed the study of triptolide-loaded nano delivery systems (NDOS) in our group during the past. It was inv......
Objective: To investigate the effects of triptolide tablet in the treatment of patients with psoriasis vulgaris. Methods......
目的 观察雷公藤多苷治疗糖尿病肾病(DN)Ⅲ期的疗效.方法 75例2型糖尿病并DNⅢ期患者,完全随机分为观察组(40例)和对照组(35例).观......
目的 观察厄贝沙坦联合雷公藤多甙对高原地区糖尿病肾病(DN)患者尿蛋白水平的影响.方法 将50例高原DN患者随机分为两组,对照组(25......
雷公藤内酯醇对多种非小细胞肺癌(non-small cell lung cancer,NSCLC)细胞系具有杀伤作用,可通过干预细胞周期、激活caspase信号通......
The long-term clinical efficacy of intracoronary stenting is limited by restenosis, which occurs in 15% to 30% of patien......
目的 探讨雷公藤甲素(TPT)预处理减轻小鼠肝脏缺血再灌注损伤的作用及其机制.方法 将C57BL/6小鼠随机分为4组(15只/组):假手术对照......
目的 通过体外实验研究雷公藤内酯醇(triptolide)对系统性红斑狼疮(systemic lupus erythematosus,SLE)患者树突状细胞(dendritic ......
目的 探讨IgA肾病(IgAN)患者外周血单个核细胞(PBMC)炎性因子分泌及自身凋亡状态,以及雷公藤甲素(TP)对其调节的相关机制.方法 取I......
目的 观察雷公藤甲素(TP)联合厄贝沙坦对2型糖尿病( T2DM)大鼠足细胞损伤的协同保护作用,并探讨其机制.方法 实验分为正常对照组(N......
Triptolide-induced Apoptosis by Inactivating Nuclear Factor-kappa B Apoptotic Pathway in Multiple My
The effect of triptolide on proliferation and apoptosis of human multiple myeloma RPMI-8226 cells in vitro,as well as th......
目的 探讨雷公藤甲素(TPT)预处理减轻小鼠肝脏缺血再灌注损伤的作用及其作用机制.方法 将60只雄性C57BL/6小鼠分成4组,每组15只.(1......
The Proteasomal Inhibitor MG132 Potentiates Apoptosis of Triptolide-Treated K562 Cells by Regulating
OBJECTIVE To explore the anticancer mechanism of triptolide in human leukemia K562 cells,and to further determine whethe......
目的观察雷公藤内酯醇(Tri)对实验性自身免疫性脑脊髓炎(EAE)小鼠小胶质/巨噬细胞极化的影响。方法60只SJL/J小鼠随机分为对照组、......
目的探讨地黄水提物配伍对雷公藤甲素所致小鼠肝脏氧化应激损伤的作用效果及可能机制。方法50只NIH小鼠随机分为空白对照组、模型......
目的:探讨雷公藤甲素对2型糖尿病小鼠耳蜗毛细胞的保护作用及机制。方法:选取Balb/c雄性小鼠,随机分为正常组、糖尿病组和雷公藤甲......
雷公藤(Tripterygium Wilfordii Hook.F)系卫矛科雷公藤属植物,雷公藤片(雷公藤的醋酸乙酯提取物片剂)是目前临床上治疗类风湿关节......
目的雷公藤甲素与脉冲射频均能有效地缓解神经病理性疼痛(NP)。文章建立脊神经结扎(SNL)大鼠NP模型,经雷公藤甲素联合脉冲射频疗法......
测试雷公藤甲素对粘虫中肠消化酶活性的影响,并对中毒试虫的中肠组织结构进行显微观察.结果表明,处理试虫脂肪酶活性在痉挛期和麻......
目的:探讨雷公藤内酯醇(TPL)对H9c2细胞缺氧/复氧(H/R)损伤的保护作用机制。方法:将体外培养的H9c2大鼠心肌细胞分为对照组、H/R组......
目的：观察雷公藤内酯醇对卵巢癌细胞株的A2780的抑制作用,以及与顺铂联合用药的协同作用,并与顺铂单独作用相比较,评价其作为抗肿瘤......
目的：研究雷公藤内酯醇（TPL）对正常人和系统性红斑狼疮（SLE）患者外周血单核细胞（PBMCs）增殖的影响,以探讨雷公藤内酯醇在SLE治疗中的意义......
目的：观察IgA肾病（IgAN）大鼠血清IgA异常糖基化的程度及雷公藤内酯醇（TP）对其影响。方法：将雄性SD大鼠随机分为正常组、IgAN模型组（模型组......
目的观察雷公藤甲素对γ-干扰素(IFN-γ)刺激后人眼球后成纤维细胞(RFs)增殖和对细胞粘附分子-1(ICAM-1)、白细胞抗原(HLA)-DR表达......
目的研究雷公藤内酯醇对人脐静脉血管内皮细胞体外培养增殖过程中纤溶酶原激活物系统蛋白表达的抑制作用。方法体外培养传三代人脐......
目的 观察雷公藤甲素（TL）对哮喘小鼠肺组织中白介素13（IL-13）和嗜酸性粒细胞趋化因子（Eotaxin）表达的影响，探讨TL治疗哮喘的作用机理。方......
目的：探讨雷公藤内酯醇对HL60细胞体外抗癌作用及其机制。方法：选用HL60细胞株，运用细胞培养、MTT法、流式细胞仪研究不同浓度雷公藤......
目的研究不同极性洗脱液对雷公藤内酯醇含量的影响。方法样品液经D101型大孔吸附树脂吸附后，分别以95％乙醇、丙酮、乙酸乙酯、乙醚、......
